Folklore Clinical Variant Interpretation MCP

Folklore Clinical Variant Interpretation MCP connects compatible AI assistants to public genomic variant, gene-disease and scientific literature evidence. Its hosted Streamable HTTP endpoint is https://api.helena.bio/folklore/v1/mcp and requires no account, API key or authentication. Setup: https://folklore.helena.bio/integrations/mcp . Public adapter: https://github.com/helena-bioinformatics/folklore-mcp .

The variant tools support GRCh38 germline nuclear SNVs and simple indels under 50 bp. Gene and literature tools return source-linked evidence with explicit limitations. Results require review by a qualified genetics professional and must not be used for diagnosis, treatment decisions or standalone clinical reporting. A literature mention does not establish pathogenicity, and no results do not establish absence of evidence.

No patient records, private case context, raw VCF/FASTQ/BAM files or batch interpretation. Apache-2.0 applies to the public protocol adapter, not the private backend or datasets. Submitted by Vladimir Mitev through an authorized AI assistant for the free editorial listing only; no advertising requested.